How to Check html minify enable programmatically Magento 2?

Magento 2 has native feature to enable html Minify from the Configuration setting in the admin panel.

Html Minification is not applied in developer mode.

To Minify html in Magento 2 via admin panel,
Go To Admin panel,
Click Stores -> Settings -> Configuration,
Select Advanced -> Developer Tab,
Open Template Settings section,
Html minify set to Yes,
Click on Save Config.

You can Check whether minify of HTML is on via programmatically,

<?php
namespace Jesadiya\HtmlMinify\Model;

use Magento\Framework\View\Asset\ConfigInterface;

class HtmlMinify
{
    /**
     * @var ConfigInterface
     */
    private $htmlMinify;

    public function __construct(
        ConfigInterface $htmlMinify
    ) {
        $this->htmlMinify = $htmlMinify;
    }

    /**
     * Check that html minification is enabled
     *
     * @return boolean
     */
    public function isHtmlMinifyEnabled()
    {
        return $this->htmlMinify->isMinifyHtml();
    }
}

Call method from the template or PHP class,
echo $isHtmlMinifyEnable = $this->isHtmlMinifyEnabled();

Output:
Boolean