How to Identify company module is active in B2B Magento 2?

You can identify Company module status like enable/disable using programmatic way.

Native Company module has a class called Magento\Company\Api\StatusServiceInterface contains the method isActive() to check the module status.

Just instantiate the interface in your class file and call method to verify the company module status.

<?php
namespace Jesadiya\CompanyModuleEnable\Model;

use Magento\Company\Api\StatusServiceInterface;

class CompanyModuleEnable
{
    /**
     * @var StatusServiceInterface
     */
    private $companyStatus;

    public function __construct(
        StatusServiceInterface $companyStatus
    ) {
        $this->companyStatus = $companyStatus;
    }

    /**
     * Return user type
     *
     * @return bool
     */
    public function isCompanyModuleActive(): ?bool
    {
        $isCompanyEnable = $this->companyStatus->isActive();
        return $isCompanyEnable;
    }
}

Call method to identify status,
echo $isCompanyActive = $this->isCompanyModuleActive();

If Output is 1, Company module is enable to work with B2B in Magento.

Output:
Boolean